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The Big Cheese is the cheese daddy of The Cheese, and a very massive, important - not to mention cheesy - cheese of great authority. It reportedly employs fat cats for the purpose of eliminating the rats that plague it and the top-secret operations of its cheesy corporation.
Who Knows? Edit
Only we ladies can know the big cheese. I guess anybody can know cheese, but when it comes to the big cheese, only women can know it. It comes with the magic that only we have.